Results 231 to 240 of about 7,127,786 (370)

Invisible spectrum: a model for minority community public engagement in cancer research. [PDF]

Res Involv Engagem
O'Grady S, Ralston JC, McKiernan E, Lanigan F, Salauddin M, Sharmin S, McVeigh T, Gallagher WM, Guerin S, Rahman A, Kolch W.   +10 more
europepmc   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

Advanced Science, EarlyView.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su, Guoqing Wu, Muya Xiong, Yuhang Wang, Junyuan Cao, Mengyuan You, Yingchun Xiang, Tianqing Nie, Minjun Li, Gengfu Xiao, Leike Zhang, Qiang Shao, Yechun Xu   +12 more
wiley   +1 more source

Democratising research evaluation: Achieving greater public engagement with bibliometrics-informed peer review [PDF]

, 2013
Gemma Derrick, Vincenzo Pavone
openalex   +1 more source

Public engagement with research reproducibility. [PDF]

PLoS Biol
Vinatier C, Kozula M, Van den Eynden V, Caquelin L, Roubik H, Stegeman I, Naudet F.   +6 more
europepmc   +1 more source

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

Balancing Act: Enabling Public Engagement with Sustainability Issues through a Multi-touch Tabletop Collaborative Game

, 2011
Alissa N. Antle, Theresa Jean Tanenbaum, Allen Bevans, Katie Seaborn, Sijie Wang   +4 more
openalex   +1 more source

Expectations and values about expanded newborn screening: a public engagement study [PDF]

, 2013
Robin Z. Hayeems, Fiona A. Miller, Yvonne Bombard, Denise Avard, June C. Carroll, Brenda J. Wilson, Julian Little, Pranesh Chakraborty, Jessica Bytautas, Yves Giguère, Judith Allanson, Renata Axler   +11 more
openalex   +1 more source

Participatory science in urban soil research: A framework for overcoming challenges and expanding public engagement. [PDF]

iScience
Paltseva AA.
europepmc   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

Surprise! Public historical geographies, user engagement and voluntarism [PDF]

, 2013
Sarah Mills
openalex   +1 more source