Results 261 to 270 of about 5,761,819 (344)

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

Advanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao, Yajie Peng, Hongyan Lei, Tianyi Wang, Huajuan Wang, Bo Wang, Jin Li, Xiaoying Li, Xuelian Xiong   +8 more
wiley   +1 more source

Social media crisis communication and public engagement during COVID-19 analyzing public health and news media organizations' tweeting strategies. [PDF]

Sci Rep
Song T, Yu P, Yecies B, Ke J, Yu H.
europepmc   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Research data use in a digital society: a deliberative public engagement. [PDF]

Int J Popul Data Sci
McGrail KM, Teng J, Bentley C, O'Doherty KC, Burgess MM.   +4 more
europepmc   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Piece of Mind: knowledge translation performances for public engagement on Parkinson's disease and dementia. [PDF]

Front Psychol
Kuhlmann N, Thomas A, Incio-Serra N, Blain-Moraes S.   +3 more
europepmc   +1 more source

Crisis Fatigue in the Digital Age: How Constant Exposure to Disasters Affects Public Attention and Engagement

BA Uri Samet
openalex   +2 more sources

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

Meaningful patient and public engagement in dissemination-embedding co-production in dementia research. [PDF]

Front Dement
de Wolf-Linder S, Kramer I, Hersperger M, Schubert M, Bächi S, Stolz M, Wolverson E, Ramsenthaler C.   +7 more
europepmc   +1 more source

Transforming Public Health Program Leadership Through Cross-Sector Collaboration, Equity-Driven Initiatives, and Evidence-Based Community Engagement Frameworks

Chizoma Amadi, Julio Frenk, Kruk Margaret, E, Freedman Lynn, P, Marmot Michael, Friel Sharon, Bell Ruth, Houweling Tanja, A, Taylor Sebastian, Farmer Paul, Beaglehole Robert, Bonita Ruth, Horton Richard, Adams Owen, Alleyne George, Asaria Perviz, Kickbusch Ilona, Gleicher David, Frenk Julio, Chen Lincoln, Bhutta Zulfiqar, A, Cohen Jordan, Crisp Nigel, Evans Timothy, Braveman Paula, Gruskin Sofia, Merson Michael, H, Black Robert, E, Mills Anne, J, Rosenfield Allan, G, Brownson Ross, C, Fielding Jonathan, E, Maylahn Christopher, M, M Hawkes, S Bennett, B, S Clampet-Lundquist, D Massey, T O'connell, K Rasanathan, M Chopra, Nutbeam Don, Ilona Kickbusch, G Laverack, Green Lawrence, W, Kreuter Marshall, W, Hunter David, J, Yach Derek, Corinna Hawkes, Gould Christine, L, Hofman Karen, J, Lucy Gilson, Nancy Krieger, Labont Ronald, Ted Schrecker, Ilona Kickbusch, Whitehead Margaret, Dahlgren Gran, Vicente Navarro, Mckee Martin, Judith Healy, Fran Baum, Walt Gill, Shiffman Jeremy, Murray Schneider Helen, F Susan, Brugha Ruair, Lucy Gilson, Marmot Michael, David Black, Porter Michael, E Teisberg, Elizabeth Olmsted, Daniels Norman, Pappas Gregory, Hadden Wilbur, C, Kozak Lola, J, Fisher George, F, Galea Sandro, Vlahov David, Mcmichael Anthony   +99 more
openalex   +1 more source