Results 41 to 50 of about 121,014 (291)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The role of science centres and museums in the dialogue between science and society [PDF]
JCOM: Journal of Science Communication, 2007 In a meta-analysis carried out in 2002, the two main associations of science centres and museums (ASTC, mainly US-centered, and ECSITE, mainly European) gathered all studies analysing the impact of science centres and museums on their local communities1.
Paola Rodari, Matteo Merzagora
doaj
Exchanges, 2021 The aim of this article is to offer an answer to the question: How can we improve public engagement in the genetically modified organisms debate? It will describe the models of Public Understanding of Science and Public Engagement with Science.
Catherine Price
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The science and society movement and the MUSE project (Italian original version) [PDF]
JCOM: Journal of Science Communication, 2007 For the purpose of this article, Science & Society (S&S) is referred to as that current of thoughts and those cultural initiatives aimed at fostering dialogue between research, scientific and technical output on the one hand and society on the other, so ...
Michele Lanzinger
doaj
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Often overlooked: formative evaluation in the development of ScienceComics [PDF]
JCOM: Journal of Science Communication, 2009 Formative evaluation should play a key role in the development of a science communication project or initiative. Such research is vital to understanding the needs and interests of the audience or participants; meeting these needs and interests helps ...
E. Weitkamp, H. Featherstone
doaj
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
, 2013 A number of researchers have been analysing apparent shifts from top-down approaches to public engagement with science and technology towards more participatory ones.
Marks, Nicola Jane
core +2 more sources