Results 51 to 60 of about 96,147 (243)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Stability in public finance as a value protected in the Constitution of the Republic of Poland of 2 April 1997 and the condition of Poland’s public finance

Acta Iuris Stetinensis
The study focuses on issues related to public finance with particular reference to values protected in the Constitution of the Republic of Poland of 2 April 1997.
Wojciech Bożek
doaj   +1 more source

The structure and trends of public expenditure in the Republic of Serbia [PDF]

Ekonomija: teorija i praksa, 2016
In modern public finance, public expenditure is becoming one of the crucial issues. Public expenditures represent funds which are necessary to finance public needs.
Kalaš Branimir, Pjanić Miloš, Andrašić Jelena   +2 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

LEVERAGING BIG DATA TECHNOLOGIES FOR ENHANCED PUBLIC PARTICIPATION IN PUBLIC FINANCIAL MANAGEMENT

Фінансово-кредитна діяльність: проблеми теорії та практики
The article is devoted to the topical issues regarding the implementation of Big Data technologies in public finance management. The application of Big Data has the potential to enhance transparency and accountability in the use of budgetary resources ...
Sergii Krynytsia, Oksana Hordei, Yuliia Kovalenko, Alla Dankevych, Andrii Boldov   +4 more
doaj   +1 more source

Affecting the Sustainability of Public Finances by the Social Measures Adopted in Romania between 2006 and 2017 [PDF]

Ovidius University Annals: Economic Sciences Series, 2017
Sustainability has become one of the most used terms in public finance assessment. This article treats the issue of sustainability of public finance in terms of social measures adopted in Romania during 2006-2017.
Trandafir Adina
doaj  

Public finances, financing and taxation in Brussels

, 2009
This publication deals with the public finances in Brussels.
Cattoir, Philippe, Vaesen, Joost, Van Der Stichele, Géraldine, Verdonck, Magali, Zimmer, Pol   +4 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source