Results 221 to 230 of about 536,150 (307)

Building better outcomes: A grounded theory approach to understanding creation and management of surgical data systems in Ethiopia. [PDF]

open access: yesPLOS Glob Public Health
Jaraczewski TJ   +9 more
europepmc   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge   +9 more
wiley   +1 more source

Context Matters: Urban Typology and Pandemic-Related Mental Health Decline in Low-Income South African Settings. [PDF]

open access: yesJ Community Psychol
Visser M   +7 more
europepmc   +1 more source

An All‐Soft Wearable Electrochemiluminescence Chip for Sweat Metabolite Detection

open access: yesAdvanced Science, EarlyView.
A wearable electrochemiluminescence chip for sweat metabolite monitoring is pioneered, integrating “all‐soft” components: a flexible closed bipolar electrode (c‐BPE) array based on laser‐induced graphene (LIG), a laser‐cut microfluidic layer for sweat collection, and deep eutectic solvents (DES)‐based conductive ionogels for ECL emission.
Wei Nie   +7 more
wiley   +1 more source

A cross-sectional survey investigating the burden of, and psychosocial factors related to, psychological distress among people living with HIV in central Tanzania. [PDF]

open access: yesBMC Psychol
Gooden TE   +12 more
europepmc   +1 more source

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao   +24 more
wiley   +1 more source

Trackable Tolerogenic Macrophages Integrate PD‐L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation

open access: yesAdvanced Science, EarlyView.
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang   +14 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

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