Results 41 to 50 of about 699,861 (259)

Public Financial Control as an Instrument of Public Administration

Сибирское юридическое обозрение, 2020
The article is devoted to the essence of public financial control and its role in the system of financial control in the management of the state. This article analyzes the existing in scientific literature approaches to the concept and contents of public
I. G. Lvova, L. V. Burnysheva
doaj  

Trends in the Development of Audit of Public Finances in the Context of Reforming the System of Public Financial Control [PDF]

Problemi Ekonomiki, 2018
The aim of the article is the theorizing of trends in the development of audit of public finances in the context of reforming the system of public financial control in Ukraine and providing practical recommendations to improve the efficiency of the ...
Krivtsova Тetiana О. , Liadova Yuliia O.   +1 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dynamics of anticancer drug use in Russian hospitals: a five-year retrospective analysis

Фармакоэкономика
Background. Pharmaceutical provision for oncology patients involves complex and controversial issues, particularly the use of oral anticancer drugs (ACDs) in day hospitals. These facilities often distribute oral medications for outpatient use, leading to
J. A. Agafonova, V. V. Omelyanovskiy
doaj   +1 more source

Development of public control in the system of financial control of the Russian Federation

IOP Conference Series: Earth and Environmental Science, 2021
Abstract The article conducts a study of the theoretical and methodological provisions and approaches to the construction and development of state-public financial control in the financial control system of the Russian Federation. The author of the work analysed the current public control system in the Russian Federation.
N L Krasyukova, O V Panina, A I Galkin, K E Lukichev   +3 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The review of the foreign experience on the financing of innovative medical technologies

Фармакоэкономика, 2020
The article presents a review of the foreign approaches to the mechanisms of financing of medical help and innovative medical technologies with the description of the implemented financial mechanisms of stimulation of innovations in foreign systems of ...
V. V. Omelyanovskiy, I. A. Zheleznyakova, T. P. Bezdenezhnykh, M. L. Lazareva, D. V. Fedyaev   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Regulatory framework of the oncological medical care provision

Фармакоэкономика, 2020
Aim. To conduct an analytical review of the regulatory legal framework on the resources provision required in medical organizations for the provision of oncological medical care based on clinical guidelines.Materials and methods.
S. N. Tishkina, V. E. Matskevich, Yu. A. Ledovskikh, E. V. Semakova, V. V. Omelyanovskiy   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source