Results 131 to 140 of about 6,596,047 (309)

Public goods

open access: yes, 2019
Supplying public goods generates costs and benefits that can be allocated among individuals in different ways. Yet leading theories of justice within liberalism fail to offer concrete guidance on how these allocations should be assessed. This chapter critically examines a number of principles of distributive justice that might be used for this purpose.
Miller, D, Taylor, I
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Moving beyond dashboards to generate data for public good-Authors' reply. [PDF]

open access: yesLancet Reg Health Southeast Asia, 2022
Yadav CP, Sharma A.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Social innovation, public good: new approaches to public sector productivity [PDF]

open access: yes
This report argues that rather than outsourcing ever more public services, governments should introduce social impact bond models within the public sector.
David Hetherington
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Moving beyond dashboards to generate data for public good. [PDF]

open access: yesLancet Reg Health Southeast Asia, 2022
Garg T, Chatterjee P.
europepmc   +1 more source

Country size and public good provision [PDF]

open access: yes
The paper studies the equilibrium size of countries. Individuals in small countries have greater influence over the nature of political decision making while individuals in large countries have the advantage of more public goods and lower tax rates.
K Staal
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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