Results 191 to 200 of about 6,596,047 (309)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Conceptualizing the public good for genomics in the global South: a cross-disciplinary roundtable dialogue. [PDF]

open access: yesFront Genet
Jiwani T   +14 more
europepmc   +1 more source

Children’s health and the ocean: a vital connection

open access: yesBMJ Paediatrics Open
Lora E Fleming   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Adaptation of the Diet Quality Questionnaire as a Global Public Good for Use in 140 Countries. [PDF]

open access: yesCurr Dev Nutr
Herforth AW   +5 more
europepmc   +1 more source

Playing with the Good Guys - A Public Good Game with Endogenous Group Formation [PDF]

open access: yes
In public good games, voluntary contributions tend to start off high and decline as the game is repeated. If high contributors are matched, however, contributions tend to stay high.
Jo Thori Lind   +3 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Animal health and welfare as a public good: what do the public think? [PDF]

open access: yesAgric Human Values
Clark B   +5 more
europepmc   +1 more source

COVID-19 heralds a new epistemology of science for the public good. [PDF]

open access: yesHist Philos Life Sci, 2021
Caniglia G   +7 more
europepmc   +1 more source

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