Results 71 to 80 of about 164,183 (315)

Public works, urban development, common goods

open access: yesTechne
The role taken by public works requires us to use them to address the need to govern the complexity of the contemporary city, focusing its development and physical transformations on shared goals.
Mario Losasso
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Public versus Private Provision of Public Goods [PDF]

open access: yes
It is well known that pure public goods are underprovided in static games with private, voluntary contributions. Public provision is usually modeled using a median voter framework, in which the public good is funded by a proportional income tax.
Sita Nataraj Slavov
core  

Spatiality of the Commons

open access: yesInternational Journal of the Commons, 2014
This editorial sets the scene for the special feature by explaining the importance of geography to the commons and its governance, critically appraising the existing literature on this theme, highlighting important contributions from recent research and ...
Timothy Moss
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Public Goods and the Distribution of Income [PDF]

open access: yes
This article addresses conceptual issues concerning the distributive incidence of public goods. Solutions depend on the specific purposes for asking the question of distributive incidence notably, assessing the extent to which various public goods should
Louis Kaplow
core  

PUBLIC OWNERSHIP IN THE LEGAL SYSTEM OF THE REPUBLIC OF CROATIA

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2009
As opposed to civil law, the theory of administrative law comprehends the concept of public good as a good (thing) which, on the one hand, is in general use, and which everyone can use according to the principle of equality.
Mario Jelušić
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

International Public Goods [PDF]

open access: yes, 2001
The theme of this paper is how to deal with the provision of international public goods (IPG), while IPG as well as public goods has been defined by its nature in consumption.
津曲, 俊英
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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