Results 51 to 60 of about 6,977,665 (334)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
SHAP Enrollment and Eligibility Activities: Implications for Process and System Modernization Under National Health Reform [PDF]
, 2012 Shares five states' experiences and best practices in using State Health Access Program grants to expand public health coverage through community-based outreach and improved eligibility and enrollment processes, as well as implications for federal ...
Brigette Courtot, Teresa A. Coughlin
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Museums Connect: Teaching Public History through Transnational Museum Partnerships
Public History Review, 2015 Museums Connect is a program funded by the US Department of State and administered by the American Alliance of Museums that sponsors transnational museum partnerships. This program provides one model for teaching public history in a transnational context,
Richard J. W. Harker
doaj +3 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Financing for new technology-based firms in Brussels
Brussels Studies, 2019 New technology-based firms are sometimes faced with financing difficulties and are able to count on various schemes and public aid to help them in their start-up phase.
Nicolas Pary, Olivier Witmeur
doaj +1 more source
, 2016 The growth of college tuition and the corresponding rise in student loan debt have become major issues of public importance. Total outstanding student debt is at least $1.3 trillion, and tuitions keep growing, even while we arguably need to invest more ...
Brooks, John R.
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Quel financement pour les jeunes entreprises technologiques bruxelloises
Brussels Studies, 2019 New technology-based firms are sometimes faced with financing difficulties and are able to count on various schemes and public aid to help them in their start-up phase.
Nicolas Pary, Olivier Witmeur
doaj +1 more source