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London Journal of Primary Care, 2014 Happy New Year for 2014. This edition's public health prose is a personal view from a public health professional in a London local authority. We will bring future messages from different public health perspectives, organisations and functions. January is the month where people are even more sheepish than usual when they bump into me as they wait on the
openaire +9 more sources
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
The Health Status of a Population estimated: The History of Health State Curves [PDF]
arXiv, 2017 Following the recent publication of our book on Exploring the Health State of a Population by Dynamic Modeling Methods in The Springer Series on Demographic Methods and Population Analysis (DOI 10.1007/978-3-319-65142-2) we provide this brief presentation of the main findings and improvements regarding the Health State of a Population.
arxiv
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Public Health: Start Here [PDF]
, 2014 CHEP: Clinical and Translational Sciences Institute’s Community Health Engagement Program IPHA: Indiana Public Health Association IPHTC: Indiana Public Health Training Center at IU Richard M.
Indiana Public Health Training Center
core
, 1988 Viewbook/course catalog of the Boston University School of Public ...
Boston University School of Public Health
core +2 more sources
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Interplay of integrins and selectins in metastasis
Molecular Oncology, EarlyView.Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva +2 more
wiley +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2007 Lyme borreliosis is uncommonly seen in Canada. Most cases have occurred in close proximity to small geographical areas where infected ticks have become established. Although few cases are seen, thousands of patients are tested yearly. Unless patients are
Canadian Public Health Laboratory Network
doaj +1 more source