Results 191 to 200 of about 17,967,355 (380)

Health and inequity in Australia

open access: yesThe Lancet Public Health, 2023
The Lancet Public Health
doaj  

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

Health-LLM: Large Language Models for Health Prediction via Wearable Sensor Data [PDF]

open access: yesarXiv
Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the capacity of LLMs to make inferences about health based on contextual information (e.g.
arxiv  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Public health is local

open access: yesThe Lancet Public Health, 2017
The Lancet Public Health
doaj   +1 more source

EpiClim: Weekly District-Wise all-India multi-epidemics Climate-Health Dataset for accelerated GeoHealth research [PDF]

open access: yesarXiv
Climate change significantly impacts public health, driving the emergence and spread of epidemics. Climate health models are essential for assessing and predicting disease outbreaks influenced by climatic variables like temperature and precipitation.
arxiv  

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

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