Results 51 to 60 of about 8,467,360 (382)

Precision Medicine for the Population-The Hope and Hype of Public Health Genomics [PDF]

open access: yesarXiv, 2022
Public health is the most recent of the biomedical sciences to be seduced by the trendy moniker "precision." Advocates for "precision public health" (PPH) call for a data-driven, computational approach to public health, leveraging swaths of genomic "big data" to inform public health decision-making. Yet, like precision medicine, PPH oversells the value
arxiv  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

HealthE: Classifying Entities in Online Textual Health Advice [PDF]

open access: yesarXiv, 2022
The processing of entities in natural language is essential to many medical NLP systems. Unfortunately, existing datasets vastly under-represent the entities required to model public health relevant texts such as health advice often found on sites like WebMD.
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Assessment of salivary cadmium levels and breast density in the Marin Women\u27s Study [PDF]

open access: yes
Background: We aimed to determine if salivary cadmium (Cd) levels had any association with breast density, hoping to establish a less invasive cost-effective method of stratifying Cd burden as an environmental breast cancer risk factor. Methods: Salivary
Benz, Christopher   +10 more
core   +2 more sources

Sacred Heart University Public Health Program Self-Study [PDF]

open access: yes, 2021
From the Introduction: The public health program began in the fall, 2018. The public health program has only one degree offered, a master’s of public health (MPH) degree with a concentration in community health.
Public Health, College of Health Professions,
core   +1 more source

PUBLIC HEALTH. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1895
n ...
openaire   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Intervention to Influence Healthy Eating Habits Among Dominican University Students: An Examination of Eating Habits [PDF]

open access: yes, 2020
Food insecurity among college students has become an issue among many universities nationwide. Campus food pantries emerged to combat this problem by providing students with a diverse selection of fresh foods.
Le, Kathy
core   +1 more source

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