Results 61 to 70 of about 18,780,434 (409)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Health Care Pollution And Public Health Damage In The United States: An Update.

open access: yesHealth Affairs, 2020
An up-to-date assessment of environmental emissions in the US health care sector is essential to help policy makers hold the health care industry accountable to protect public health. We update national-level US health-sector emissions.
Matthew J. Eckelman   +5 more
semanticscholar   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

PUBLIC HEALTH. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1895
n ...
openaire   +1 more source

Counterfeiting and Public Health [PDF]

open access: yes, 2012
*** This material is copyrighted and any download is for personal use only *** The original article is published in Criminal Enforcement of Intellectual Property: A Handbook of Contemporary Research edited by Christophe Geiger © 2012 Edward ...
MATTHEWS, DN
core  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Public Conversations & Public Solutions: Making Health and Health Care Better in Minnesota [PDF]

open access: yes, 2012
Between April and July 2012, more than 2,000 Minnesotans came together in more than 40 community conversations called Citizen Solutions to share their concerns about and ideas for fixing health care in the state.The results of the meeting (summarized in ...

core  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Public health in Calcutta [PDF]

open access: yes, 2003
'Wellcome History' is an easy and regular channel of communication between all Wellcome historians.

core  

Scaring the public: fear appeal arguments in public health reasoning [PDF]

open access: yes, 2012
The study of threat and fear appeal arguments has given rise to a sizeable literature. Even within a public health context, much is now known about how these arguments work to gain the public's compliance with health recommendations. Notwithstanding this
Cummings, L
core   +2 more sources

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