Results 61 to 70 of about 3,329,282 (264)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Evaluating a train-the-trainer approach for improving capacity for evidence-based decision making in public health [PDF]

open access: gold, 2015
Laura Yarber   +9 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Living in detention: a matter of health justice

open access: yesThe Lancet Public Health, 2020
The Lancet Public Health
doaj   +1 more source

Social Media– and Internet-Based Disease Surveillance for Public Health

open access: hybrid, 2020
Allison E. Aiello   +2 more
openalex   +1 more source

Impact of COVID 19 response on public health literacy and communication [PDF]

open access: diamond, 2022
Namrata Hange   +8 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Education: a neglected social determinant of health

open access: yesThe Lancet Public Health, 2020
The Lancet Public Health
doaj   +1 more source

COVID-19—break the cycle of inequality

open access: yesThe Lancet Public Health, 2021
The Lancet Public Health
doaj   +1 more source

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