Results 111 to 120 of about 3,011,326 (280)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Health services in the USSR [PDF]

open access: yes, 1971
As Malta's participant at the recent World Health Organization Advanced Course in Health Planning held in the Soviet Union, the author had the opportunity of observing certain characteristic features of the Soviet public health system. Health services in
Fenech, Peter A.
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

The prevalence of hepatitis B in Chinese general population from 2018 to 2022: a systematic review and meta-analysis

open access: yesBMC Infectious Diseases
Background Within China, Hepatitis B virus (HBV) infection remains widely prevalent and one of the major public health problems. There have been only two previous estimates of its prevalence at the population level in China, with the latest survey ...
Shuwen Bai   +4 more
doaj   +1 more source

The Accessibility and Acceptability of Health Services in Remote Rural Areas

open access: yesAsia Pacific Journal of Health Management
Health services depend on community facilities and infrastructure, particularly in rural areas. If facilities and infrastructure are not improved, it is feared that equitable distribution, including accessibility and acceptability of health services ...
Mutiara Ramadhani   +4 more
doaj   +1 more source

Application Areas of the Shared Service Concept within the Romanian Health System [PDF]

open access: yes
The Romanian healthcare system can be characterized by chronic under financing, leading to poor services towards the patients, corruption and high debts of the public institutions towards their suppliers. In order to cope with the situation, the Romanian
Martin WENDEROTH
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Positive deviance/hearth intervention in collaboration between academia and NGOs: a realist evaluation

open access: yesBMC Public Health
Numerous NGOs and donors from high-income countries (HICs) offer diverse funding to assist LMICs. A collaborative effort in nutrition programs in urban communities was conducted by an international NGO with a local university, representing the NGO’s ...
Nuzulul Kusuma Putri   +2 more
doaj   +1 more source

Governance of communicable disease control services : a case study and lessons from India [PDF]

open access: yes
The authors study the impact of governance and administrative factors on communicable disease prevention in the Indian state of Karnataka using survey data from administrators, frontline workers, and elected local representatives.
Das Gupta, Monica   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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