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CONTRIBUTION OF STUDENT HEALTH SERVICES TO PUBLIC HEALTH [PDF]

JAMA: The Journal of the American Medical Association, 1922
A health service is neither an institution of philanthropy nor an organization for the promotion of paternalism. It strives to cooperate, not to compete, with the medical profession. It augments rather than decreases the practice of local physicians. It has nothing to do with either compulsory health insurance or contract practice. It functions solely
openaire   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Individual-level characteristics and geospatial factors associated with cervical cancer screening participation in Alberta, Canada: a population-based cross-sectional study

BMC Public Health
Background Cervical cancer is the fourth most common cancer in women worldwide. Effective primary prevention with human papillomavirus vaccination and secondary prevention with screening can prevent most cervical cancer cases.
Jessica Law, Geneviève Jessiman-Perreault, Amanda Alberga Machado, Linan Xu, Bonnie Chiang, Huiming Yang, Lisa Allen Scott, Rizwan Shahid, Curtis Mabilangan, Alvin Li, Kamala Adhikari, Gary Teare   +11 more
doaj   +1 more source

Population-wise incidence and outcomes of patients requiring invasive and non-invasive mechanical ventilation in China: a nationwide retrospective analysis by age, sex, and comorbidity

Annals of Intensive Care
Background: Mechanical ventilation is a critical yet labor-intensive medical resource with limited availability. However, population-based data on its utilization and outcomes remain scarce in China.
Maomao Cao, Rong Liufu, Boyang Wang, Wei Pan, Hongda Chen, Longxiang Su, Yun Long, Xiang Zhou, Li Weng, Bin Du   +9 more
doaj   +1 more source

A four-domain approach of frailty explored in the Doetinchem Cohort Study

BMC Geriatrics, 2017
Background Accumulation of problems in physical, psychological, cognitive, or social functioning is characteristic for frail individuals. Using a four-domain approach of frailty, this study explored how sociodemographic and lifestyle factors, life events
Sandra H van Oostrom, Daphne L van der A, M Liset Rietman, H Susan J Picavet, Manon Lette, W M Monique Verschuren, Simone R de Bruin, Annemieke M W Spijkerman   +7 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Association between socio-economic status and outcomes among critically ill Covid-19 adult patients in France

Annals of Intensive Care
Introduction: Socio-economic inequalities have been identified as a potential risk factor for adverse outcomes in patients with Covid-19. In the specific setting of critical care, data are currently more controversial.
Diane Naouri, Naïke Bigé, Tai Pham, Martin Dres, Gaëtan Béduneau, Alain Combes, Antoine Kimmoun, Alain Mercat, Albert Vuagnat, Matthieu Schmidt, Alexandre Demoule, Matthieu Jamme   +11 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source