Results 141 to 150 of about 1,543,394 (233)
Effectiveness of Organized Strategies to Enhance Access to Preventive Oral Cancer Screening Among High‐Risk Individuals in Brazil: A Randomized Clinical Trial in Primary Care
International Journal of Cancer, EarlyView.This randomized clinical trial evaluated the performance of organized risk‐based strategies to expand access to cancer preventive oral examination among vulnerable populations within the public health system of Rio de Janeiro, Brazil. Compared with an opportunistic approach, the organized invitation‐based oral cancer screening approaches systematically Marcia Frias Pinto Marinho, Keith Bullia da Fonseca Simas, Patrícia Vinas Heras, Claudia Aparecida Serra da Cruz, Amanda Martins dos Santos Bessa, Mário José Romãnach, Aline Corrêa Abrahão, Maria Augusta Visconti, Michelle Agostini +8 morewiley +1 more sourcePancreatic Cancer Early Detection Biomarkers for High‐Risk Individuals: Insights From the PRECEDE Consortium
International Journal of Cancer, EarlyView.ABSTRACT
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...Christine Worthington, Maria Raitses‐Gurevich, Giulio Innamorati, Phil A. Hart, Thomas M. Wilkie, Noam Tau, Dana Brin, Doron Yablecovitch, Ido Laish, Dove Keith, Kurt Giles, Jennifer B. Permuth, Diane M. Simeone, George Zogopoulos, Randall E. Brand, John J. Graff, Julie Earl, On behalf of the PRECEDE Consortium, Nikhil Agarwal, Laufey Amundadottir, Michelle Anderson, Ajay Bansal, Todd Bauer, Georg Beyer, Yan Bi, Erkut Borazanci, Randy Brand, Teri Brentnall, Carol Burke, Darren Carpizo, Saurabh Chawla, Daniel Chung, Sourat Darabi, Michael Demeure, Timothy Donahue, Julie Earl, Whitney Espinel, James Farrell, Vigdís Fjóla Stefánsdóttir, Jared Forrester, Eitan Friedman, Paul Franklin, Srinivas Gaddam, Ana García García de Paredes, Steven Gallinger, Talia Golan, Ora Gordon, Robert Grant, William Greenhalf, Eli Marie Grindedal, Aaron Grossberg, Brenda Hafers, Heather Hannon, Sigurdís Haraldsdóttir, Stefán Haraldsson, Peter Hegyi, Melissa Hogg, Amy de Haar‐Holleman, Susan Hong, Greg Idos, Edward Kim, Fay Kastrinos, Bryson Katona, Vivek Kaul, Derk Klatte, Kelsey Klute, Kimberly Ku, Sonia Kupfer, Rich Kwon, Rosario Ligresti, James James Lin, Wei‐Chih (David) Liao, Aimee Lucas, Nipun Merchant, Andrew Metz, Whitney Maxwell, James McLoughlin, Sodech Miclette, Xavier Molero, Leticia Moreira, Takuji Okusaka Chigusa Morizane, Joanne Ngeow, Salvatore Paiella, Jennifer Permuth, Maricel Purcell, Joshua Raff, Vineet Rolston, Intan Schrader, Rosie Sears, Yan‐Shen Shan, Diane Simeone, Jens Siveke, Brett Sheppard, Tyler Stevens, Elena Stoffel, Dan Sussman, Margaret Tempero, Jose Trevino, Jennifer Valerin, Eva Vaquero, Ray Wadlow, Garrett Ward, David Weinberg, Ronald Wolf, Dana Zakalik, George Zogopoulos +105 morewiley +1 more sourceVascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.Abstract Objective
Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka +11 morewiley +1 more sourceThe FemTech revolution: Unlocking the potential of new technology for optimizing pregnancy outcomes in low‐ and middle‐income countries and remote areas
International Journal of Gynecology &Obstetrics, EarlyView.Abstract
Maternal and neonatal mortality and morbidity rates uncover major global health disparities. Despite ongoing efforts, the rates of maternal and neonatal complications remain substantially higher in low‐ and middle‐income countries (LMICs) compared to high‐income countries (HICs). These high rates are the result of several unmet needs in LMICs, Nir Melamed, Hema Divakar, Mahesh Choolani, Fionnuala M. McAuliffe, Lin Foo, Hassan Shehata, Gabriel Jones, Vyta Senikas, Eline M. Van der Beek, Nandita Palshetkar, Gabriele Saccone, Vincenzo Berghella, Mauricio A. Cuello, Justin Konje, Bhaskar Bhatt, Augusto Cam, Moses Obimbo, Aris Papageorghiou, Moshe Hod, on behalf of the FIGO Committee on Women's Health and Technology +19 morewiley +1 more sourceIntegrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis
iMeta, EarlyView.Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.Yi Jin, Frederick Clasen, Fernando Garcia‐Guevara, Sania Arif, Robert Schierwagen, Gholamreza Bidkhori, Michael Praktiknjo, Maximilian J. Brol, Frank E. Uschner, Florence A. Castelli, Nicolas Pons, Benoit Quinquis, Nathalie Galleron, Kevin Da Silva, Christophe Junot, Debbie L. Shawcross, David L. Moyes, Rajiv Jalan, S. Dusko Ehrlich, Vishal C. Patel, Jonel Trebicka, Saeed Shoaie +21 morewiley +1 more sourceAssociation Between Caries Risk and Public Water Fluoridation in Balsas, Maranhão: A Cross-Sectional Study. [PDF]
Healthcare (Basel)Pes LVB, Mateus AR, Horta HF, Lopes AO, Justo BRL, Narciso JVA, Gabriel M, Júnior SAGF, Moura JR, Sampaio C, Mota AJD, Garcia WG, Antoniali C. +12 moreeuropepmc +1 more sourceDecidual macrophage‐mediated ferroptosis in trophoblasts leads to recurrent spontaneous abortion
iMeta, EarlyView.Decidual macrophages from recurrent spontaneous abortion (RSA) patients promote trophoblast ferroptosis and impair trophoblast cell function. Mechanistically, the CXCL2/NF‐κB/HMOX1 axis mediates this effect. Conversely, trophoblasts co‐cultured with RSA decidual macrophages induce pro‐inflammatory macrophage polarization through IL‐6/JAK2/STAT3 ...Xin Chen, Xueqin Ma, Pengcheng Pang, Heng Zhou, Ruohan Li, Yan He, Yan Zhang, Jing Yang, Qianlin Song, Qingsong Ye +9 morewiley +1 more source