Results 91 to 100 of about 269,391 (332)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Editorial: Public health promotion and medical education reform, volume III

Frontiers in Public Health
Zeng Xiaoyun
exaly   +3 more sources

Education and training in health promotion: theory and methods

, 1996
Health promotion is evolving into a discrete concept with a definition commonly understood by all who use the term. This is to be distinguished from the kind of umbrella approach used by all manner of groups and disciplines to define their intentions or ...
KELLEHER, CECILY
core   +1 more source

Master of Public Health Concentrations in Global Health in 2020: Preparing Culturally Competent Professionals to Address Health Disparities in the Context of Globalization

, 2021
During the 2019-2020 academic year, 37 (17%) of 223 Council on Education for Public Health (CEPH) accredited or applicant schools and programs of public health offered Master of Public Health (MPH) degrees with concentrations in general global health ...
Malouin, Rebecca, Waggett, Caryl E., Zeraye, Helen A., Jacobsen, Kathryn H., Gartin, Meredith, Bisesi, Michael S.   +5 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Health Promoting Behaviors and their Relationship with Self-efficacy of Health Workers

نشریه پرستاری ایران, 2017
Background & Aims: Health promoting behaviors are one of the main criteria for determining health. Nowadays, it is believed that for being successful in behavior change and health promotion, people should have sufficient self-efficacy.
M Abdolkarimy, M Zareipour, H Mahmoodi, S Dashti, R Faryabi, E Movahed   +5 more
doaj  

Role of schools of public health libraries in health promotion/health education: report of a study conducted at the University of Michigan School of Public Health Library [PDF]

by Mary Townsend, Theresa Covington."The School of Public Health Library at the University of Michigan entered into an agreement in February 1982 with Raven Systems and Research, Inc.

core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Comparing E-learning and Lecture-Based Education in Control of Nosocomial Infections

پیاورد سلامت, 2016
Background and Aim: Effective educational programs, is one of the most basic methods in prevention of Nosocomial infection. This study aimed to compare the effects of E-learning versus lecture-based education in prevention of Nosocomial infections among ...
Mina Sadat Hashemiparast, Roya Sadeghi, Mohammadreza Ghaneapur, Kamal Azam, Azar Tol   +4 more
doaj