Results 101 to 110 of about 706,818 (294)
Advanced Science, EarlyView.Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen +14 more
wiley +1 more source
Sustainability of healthcare financing in the Western Balkans : an overview of progress and challenges [PDF]
This paper explores the major challenges to the sustainability of health sector financing in the countries of the Western Balkans - Albania, Bosnia and Herzegovina, the Former Yugoslav Republic of Macedonia, Montenegro, Serbia and the province of Kosovo.
Bredenkamp, Caryn, Gragnolati, Michele
core
Advanced Science, EarlyView.Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka +3 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2018 BackgroundLeprosy is a major public health problem in many low and middle income countries, especially in India, and contributes considerably to the global burden of the disease.
Anuj Tiwari +4 more
doaj +1 more source
Time to death and health expenditure of the Czech health care system [PDF]
Growing concern about future sustainability of public budgets in the context of population ageing has given rise to a large debate on the role of age in the context of health care expenditure.
Kateřina Pavloková
core +1 more source
Advanced Science, EarlyView.4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang +7 more
wiley +1 more source
RECONSIDERING THE FUNDING SOURCES FOR THE HEALTH SYSTEM IN ROMANIA [PDF]
Annals of the University of Oradea: Economic Science, 2010 An optimal health system must ensure that all citizens have free access to medical services, and to determine the effective use of funds. We therefore reach the conclusion that the health financing system that best meets the optimal criteria is the ...
BUNESCU LILIANA, MIHAIU DIANA MARIETA
doaj
Southern African customs union revenue, public expenditures and HIV/AIDS in BLNS countries
South African Journal of Economic and Management Sciences, 2014 This study investigates how revenue from the Southern African Customs Union (SACU) common revenue pool affects efforts to contain HIV/AIDS in Botswana, Lesotho, Namibia and Swaziland (BLNS countries).
Harold Ngalawa
doaj +1 more source
Advanced Science, EarlyView.This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang +6 more
wiley +1 more source
Advanced Science, EarlyView.Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng +14 more
wiley +1 more source