Results 131 to 140 of about 706,818 (294)

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong   +13 more
wiley   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

open access: yesAdvanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman   +15 more
wiley   +1 more source

Impact of Public Health Expenditure on Health Outcome: Evidence from India

open access: yesOnline Journal of Health & Allied Sciences
This study was designed to examine the impact of public health expenditure on health outcome in India. The study used time series data for the period from 1990 to 2024.
Jyotsnali Chetia
doaj  

The impact of health care expenditure on health indicators: an empirical analysis in middle income countries

open access: yesPayesh, 2015
Objective (s): This paper investigates the impact of health expenditure on health status for 68 middle income countries over the period 1980-2011. Methods: Random effects panel data regression model was fitted to determine the effects of health care ...
Seyed Kamal Sadeghi   +1 more
doaj  

The composition of public expenditure and growth : a small-scale intertemporal model for low-income countries [PDF]

open access: yes
This paper presents a small-scale intertemporal model of endogenous growth that accounts for the composition of public expenditure and externalities associated with public capital.
Bayraktar, Nihal   +1 more
core  

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

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