Results 161 to 170 of about 22,822,786 (291)

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

open access: yesAdvanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang   +10 more
wiley   +1 more source

Public Health Expenditure for Universal Health Coverage in Ghana

open access: yes
Ghana has made substantial progress toward universal health coverage (UHC) andcompares relatively well in health outcomes among its economic peers. Internationalcomparisons of government current health expenditure suggest that Ghana spends less than the sub-Saharan African norm for its income level.
Agyekum, Enoch Oti   +5 more
openaire   +2 more sources

DyProL: Dynamic Ensemble Representation Learning for Protein–Nucleic Acid Binding Site Prediction

open access: yesAdvanced Science, EarlyView.
Protein function is represented as a dynamic conformational ensemble rather than a single static structure. A multi‐conformation geometric attention framework aligns, clusters, and learns representative states to capture residue‐ and ensemble‐level signals. Integrating structural dynamics improves interpretable protein‐NA binding prediction and reveals
Pengpai Li   +3 more
wiley   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

open access: yesAdvanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen   +7 more
wiley   +1 more source

A Scalable Spin‐Coating Strategy for Mesoporous Gold Thin Films toward miRNA Detection

open access: yesAdvanced Science, EarlyView.
A scalable spin‐coating strategy produces uniform mesoporous Au thin films with tunable thickness and high electroactive surface area on transparent substrates. The resulting architecture enables label‐free, amplification‐free detection of ovarian cancer‐associated miRNA hsa‐miR‐200c‐3p from 1 aM to 10 pM, achieving a 1.72 aM detection limit with high ...
Aditya Ashok   +8 more
wiley   +1 more source

The Depression and Public Health Expenditures

open access: yesAmerican Journal of Public Health and the Nations Health, 1934
openaire   +3 more sources

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

open access: yesAdvanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang   +8 more
wiley   +1 more source

Gasto federal en salud en población no asegurada: México 1980-1995 Federal expenditure in health for non-insured population: Mexico 1980-1995

open access: yesSalud Pública de México, 1997
Las crisis económicas que han afectado a México desde principios de los años ochenta han influido de manera determinante en el gasto público en bienestar social y, por lo mismo, en el gasto público en salud.
ALEJANDRO LARA   +3 more
doaj  

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