Results 161 to 170 of about 78,054 (295)
Advanced Science, EarlyView.This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction
Advanced Science, EarlyView.We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen +3 more
wiley +1 more source
America's health care problem: an economic perspective [PDF]
Soaring health care expenditures and the large number of uninsured Americans-now estimated at 35 million-have received much public attention in recent years. The widespread concerns have led to demands for substantial reform of the U.S.
Beverly J. Fox +2 more
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Efficient Direct Recycling of Spent Batteries: Integrated Lithiation and Delamination
Advanced Science, EarlyView.An integrated process for the delamination and relithiation of spent cathodes, LixNi0.6Co0.2Mn0.2O2 and LixFePO4, under open‐air conditions is proposed. The transition‐metal (Ni) oxidation state in the cathode is reduced by the oxidation of diethylene glycol, facilitating relithiation. Glycol aldehyde formation induces 100% electrode delamination.
Jeonghwan Song +11 more
wiley +1 more source
Iranian Household Financial Protection against Catastrophic Health Care Expenditures
Iranian Journal of Public Health, 2012 Background: Protecting households against financial risks is one of objectives of any health system. In this regard, Iran's fourth five year developmental plan act in its 90th article, articulated decreasing household's exposure to catastrophic health ...
M Nekoei Moghadam +4 more
doaj
Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design
Advanced Science, EarlyView.A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram +4 more
wiley +1 more source
Public and Private Expenditures on Health in the Presence of Inequality and Endogenous Mortality: A Political Economy Perspective [PDF]
In this paper we study an overlapping-generations model in which agents� mortality risks, and consequently impatience, are endogenously determined by private and public investment in health care.
Elizabeth Richardson, Radhika Lahiri
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NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Advanced Science, EarlyView.Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source
Public Health Expenditure and Spatial Interactions in a Decentralized National Health System
One of the limitations of cross-country health expenditure analysis refers to the fact that the financing, the internal organization and political restraints of health care decision-making are country-specific and heterogeneous. Yet, a potential solution
Joan Costa Font, Jordi Pons Novell
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Demand for Public Health Care in Pakistan [PDF]
A health care demand model is estimated for each province in Pakistan to explain the outpatient visits to government hospitals over the period 1989–2006.
Wimal Rankaduwa +2 more
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