Results 61 to 70 of about 831,551 (333)

Prevalence and determinants of the use of self-tests by members of the public: a mixed methods study [PDF]

, 2006
Background Self-tests can be used by members of the public to diagnose conditions without involving a doctor, nurse or other health professional. As technologies to design and manufacture diagnostic tests have developed, a range of self-tests have ...
A Figueiras, A Scott, Angela Ryan, British Medical Association Board of Science, C Bradley, C Pope, CA Ford, E O'Brien, F Payne, FA Stevenson, Human Genetics Commission, J Erwin, J Kitzinger, J Ritchie, JM Morse, LJ Haddow, MC Weiss, MH Merson, MQ Patton, Office of Population Censuses and Surveys, Parliamentary Office of Science and Technology, R Krueger, S Coster, S Wilson, Sheila Greenfield, Sue Wilson, YouGov Limited   +26 more
core   +4 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Nurse-Family Partnership and Geography: An Intersectional Perspective

Global Qualitative Nursing Research, 2020
Nurse-Family Partnership is a targeted public health intervention program designed to improve child and maternal health through nurse home visiting. In the context of a process evaluation, we posed the question: “In what ways do Canadian public health ...
Karen A. Campbell, Karen MacKinnon, Maureen Dobbins, Susan M. Jack,   +4 more
doaj   +1 more source

Transforming Health Care in South Africa: A Summary Evaluation of The Atlantic Philanthropies' Nursing Programme [PDF]

, 2014
Nursing in South Africa has long been neglected, in part because of the turmoil brought about by apartheid. This lack of attention has had dire implications for the vast majority of South Africans who rely on the public health system for health care.From

core  

Three issues for mental health nurse educators preparing new preregistration programmes [PDF]

, 2020
Universities across the UK must develop and have in place new preregistration programmes by 2020. Unlike in the rest of the world, where initial nurse preparation is generic, preregistration education in the UK allows students to specialize in one of ...
Barlow, Emily-May, Chouliara, Zoe, Ion, Robin, Patrick, Leanne   +3 more
core   +4 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Family eating and physical activity practices among African American, Filipino American, and Hispanic American families: Implications for developing obesity prevention programs

, 2017
Overweight and obesity among children and adults is well-documented as an escalating problem. The purpose of this study is to determine the blood pressure, self-esteem, and eating and physical activity practices among African Americans, Filipino ...
Porter, Luz Sobong
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Kouluterveydenhoitajan merkitys ekaluokkalaisen terveyden edistämisessä : Opas ekaluokkalaisen huoltajille [PDF]

, 2014
Opinnäytetyön tarkoituksena on laatia kouluterveydenhoitajan työnkuvaa ja kouluterveydenhuoltoa käsittelevän kirjallisuuden, tutkimusten ja omien kokemusten pohjalta ekaluokkalaisten huoltajille jaettava opas.
Hautamäki, Jenni, Rosenberg, Noora
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source