Results 131 to 140 of about 2,676,824 (308)
BMC Cancer, 2018 Background Survival rates for upper gastrointestinal (GI) cancer are poor since many are diagnosed at advanced stages. Fast track endoscopy has been introduced to prompt diagnosis for patients with alarm symptoms that could be indicative of upper GI ...
Sanne Rasmussen +5 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Experience of Using Information Systems in Public Health Practice: Findings from a Qualitative Study
Online Journal of Public Health Informatics, 2014 Objective Data collection and management by local health departments (LHDs) is a complex endeavor, complicated by system level and organizational factors.
J. Vest, L. M. Issel, Sean Lee
semanticscholar +1 more source
, 2009 The aim of the consultation was to collect views on how the European Union can contribute to reducing health inequalities both within and between member states.
Institute of Public Health in Ireland (IPH)
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Shaping the future: applying therapy research to practice
, 2012 In these challenging financial times the use of research as a basis for effective health and social care cannot be overstated. \u27Shaping the Future\u27, a joint Public Health Agency and University of Ulster workshop (27 January) takes a fresh look at ...
Public Health Agency
core +1 more source
BMC Public Health, 2016 Background Women in several countries will soon be covered by two preventive programmes targeting cervical cancer: HPV vaccination and cervical screening. The HPV vaccines are expected to prevent approximately 70 % of cervical cancers.
Mie Sara Hestbech +4 more
doaj +1 more source
Ethics, Practice, and Research in Public Health
American Journal of Public Health, 2004 Ethical issues that can arise in distinguishing public health research from practice are highlighted in 2 case studies—an investigation of a tuberculosis outbreak in a prison and an evaluation of a program for improving HIV prevention services. Regardless of whether such public health investigations represent research or practice, we see a need for ...
Kathleen M, MacQueen, James W, Buehler
openaire +3 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source