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Survivors of childhood cancers can face life-long health risks. In this study we describe the prevalence of childhood cancer in Canada by type, geographic region, year, age group and sex, using publicly available data in the Cancer in Young People in ...
Katherine McKenzie +4 more
doaj +1 more source
Key factors for sustainability of regional animal health networks: CaribVET example [PDF]
CaribVET is a collaborative network of veterinary services, research institutes and regional/international organizations whose objective is to improve animal and veterinary public health in the Caribbean. Set up on a bottom-up process about 15 years ago,
Faverjon, Céline +6 more
core
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Recreational screen time and mental health among Canadian children and youth
BackgroundHigher amounts of recreational screen time have been associated with mental ill-health among children and youth. We examined the association between meeting the 24-Hour Movement Guideline’s recreational screen time ...
Stephanie Toigo +5 more
doaj +1 more source
HEALTH VALUE IN FOOD SAFETY SURVEILLANCE INITIATIVES [PDF]
Recognizing the increasing concern about the potential health effects of genetically modified foods, this research provides a framework for economic value of monitoring genetically modified food for their potential long-term human health effects. This is
Amanor-Boadu, Vincent +2 more
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Public Health Disease Surveillance Networks
ABSTRACTZoonotic infections are important sources of human disease; most known emerging infections are zoonotic (e.g., HIV, Ebola virus, severe acute respiratory syndrome, Nipah virus, and enteropathogenicEscherichia coli) and originated as natural infections of other species that acquired opportunities to come in contact with humans.
openaire +2 more sources
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
Background: COVID-19 vaccination efforts are critical in mitigating the impact of the virus, but despite proven safety and efficacy, vaccination rates among children in Canada are lower than in adults, prompting a need to explore determinants of ...
David Guan +3 more
doaj +1 more source

