Results 61 to 70 of about 1,859,448 (316)

Differential effect of China’s Zero Markup Drug Policy on provider-induced demand in secondary and tertiary hospitals

Frontiers in Public Health
Following the marketization of China’s health system in the 1980’s, the government allowed public hospitals to markup the price of certain medications by 15% to compensate for reduced revenue from government subsidies.
Xiaoxi Zhang, Armand Zimmerman, Hongyu Lai, Yanyan Zhang, Zhongyi Tang, Shenglan Tang, Osondu Ogbuoji, Osondu Ogbuoji   +7 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Preoperative Anxiety and Associated Factors Among Adult Patients Undergoing Elective Surgery at the Public Hospitals in Bahir Dar City, Ethiopia: A Cross‐Sectional Study

Health Science Reports
Background and Aims Preoperative anxiety affects many patients, impacting both their readiness for surgery and their postoperative recovery. A multi‐center study on preoperative anxiety is limited to the study area.
Wubet Tsega, Tesfaye Ayenew, Zemenu Shiferaw Yadita   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Indigenous identification in hospital separations data: quality report [PDF]

, 2013
This report presents the results of a study on the quality of Indigenous identification in administrative records of hospitalisations in public hospitals in Australia.An estimated 88% of Indigenous patients were correctly identified in public hospital

core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005. [PDF]

, 2007
BACKGROUND: Adverse drug reactions (ADRs) are a frequent cause of mortality and morbidity to patients worldwide, with great associated costs to the healthcare providers including the NHS in England.
Majeed, Azeem, Patel, M, Car, J, Molokhia, Mariam, Mariam Molokhia, Janakan Srishanmuganathan, Patel, H, Bell, Derek, Car, Josip; id_orcid, Srishanmuganathan, Janakan, Car, Josip, Majeed, A, Mitesh Patel, Patel, Hitesh, Josip Car, Bell, D, Molokhia, M, Patel, Mitesh, Derek Bell, Srishanmuganathan, J, Hitesh Patel, Azeem Majeed   +21 more
core   +1 more source

Relationship between Strategy and Organizational Structure: A Comparative Study between Public and Private Hospitals of Tehran 2012

بیمارستان, 2014
Background: Strategy is one of the important factors affecting the organizational structure. Taking the relationship between these two mentioned factors into consideration is essential. This study surveys the relationship between organizational structure
Sakineh Alizadeh, Mohammad Reza Maleki, Rahim Khodayari Zarnaq, Sajad * . Darzi Ramandi, Ahmad Sadeqi   +4 more
doaj  

The CEO Experience in Victorian Public Hospitals: Challenges and strategies for leadership stability

Asia Pacific Journal of Health Management
Leadership stability is increasingly recognised as critical to hospital performance and reform continuity, yet CEO turnover in healthcare is among the highest globally.
Michelle Pizer
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source