Results 121 to 130 of about 9,238,248 (387)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Barriers to Care Amongst Rural Indigenous Mayans in Guatemala’s Western Highlands [PDF]

open access: yes, 2016
Information presented here is based on 5-week volunteering experience at Primeros Pasos clinic in the rural Palajunoj Valley outside the city of Quetzaltenango, Guatemala. Almost all of the patient population is rural, indigenous Quiche Maya.
Butala, Nirali
core   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Bifurcation analysis and global dynamics of a mathematical model of antibiotic resistance in hospitals [PDF]

open access: yesarXiv, 2016
Antibiotic-resistant bacteria has posed a grave threat to public health by causing a number of nosocomial infections in hospitals. Mathematical models have been used to study the transmission of antibiotic-resistant bacteria within a hospital and the measures to control antibiotic resistance in nosocomial pathogens.
arxiv  

Transparency and Public Reporting Are Essential for a Safe Health Care System [PDF]

open access: yes, 2010
Compares three approaches to spurring hospitals to improve patient safety and argues that public reporting of performance and feedback to providers is more effective than regulation and accreditation or financial ...
Lucian L. Leape
core  

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Factors influencing e-health implementation by medical doctors in public hospitals in Zimbabwe

open access: yesSouth African Journal of Information Management, 2018
Background: Improving access to health care services in both developed and developing countries through information communication technology (ICT) has been getting particular attention from government, medical researchers and practitioners. This has seen
S. S. Furusa, A. Coleman
semanticscholar   +1 more source

Demand for Public Health Care in Pakistan [PDF]

open access: yes
A health care demand model is estimated for each province in Pakistan to explain the outpatient visits to government hospitals over the period 1989–2006.
Adiqa K. Kiani   +2 more
core  

Developing reference plans for evaluating global clinical trials credentialing and PSQA systems

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To develop a practical framework for creating a diverse set of validated reference plans (varying in complexity) and implement a workflow to introduce beam modeling, calibration, and delivery errors into the reference cohort to test and compare various dosimetry audit methodologies.
Fre'Etta M. D. Brooks   +13 more
wiley   +1 more source

The Health Sector Evolution Plan and the Technical Efficiency of Public Hospitals in Iran

open access: yesIranian Journal of Public Health, 2019
Background: Iranian public hospitals have been excessively changing during the healthcare reform since 2014. This study aimed to examine the technical efficiency of public hospitals during before and after the implementation of Health Sector Evolution ...
E. Kakemam, H. Dargahi
semanticscholar   +1 more source

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