Results 161 to 170 of about 1,515,540 (311)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The Integral Role of Nurses in Ensuring Well-Designed and Functional New Public Hospitals: A Qualitative Study. [PDF]

Int Nurs Rev
Segev R, Leibovich-Nassi I, Perepech A, Adler I, Danieli T.   +4 more
europepmc   +1 more source

Fiscal Shenanigans, Targeted Federal Health Care Funds, and Patient Mortality [PDF]

The federal government spends billions of dollars each year on programs designed to increase the resources available to hospitals that serve the poor. This paper explores the intended and unintended effects of such targeted funds.
Douglas Staiger, Katherine Baicker
core  

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Needlestick and sharps injuries and its preventive implications among cleaners in tertiary public hospitals, Ethiopia. [PDF]

BMC Public Health
Tolera ST.
europepmc   +1 more source

Indigenous identification in hospital separations data: quality report [PDF]

This report presents the results of a study on the quality of Indigenous identification in administrative records of hospitalisations in public hospitals in Australia.An estimated 88% of Indigenous patients were correctly identified in public hospital

core  

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Magnitude of Adverse Birth Outcomes and Predictors Among Newborns Delivered at Public Hospitals in Benadir Region, Somalia. [PDF]

J Epidemiol Glob Health
Mohamoud JH, Warsame ZA, Ibrahim MM, Adam MH, Mohamed AMS, Hersi SA, Asowe HA, Garba B, Dirie NI, Hassan J, Moalim SA, Ahmed MM, Hassan Orey FA, Abdi AA.   +13 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Indoor occupational risk assessment of traffic-related nitrogen dioxide in public hospitals, Alexandria, Egypt. [PDF]

J Egypt Public Health Assoc
Abd El-Latef EMA, Kamel AA, Zaki GR, Issa AI, Abdelraheem A.   +4 more
europepmc   +1 more source