Results 301 to 310 of about 9,137,637 (404)
The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang+16 more
wiley +1 more source
Antecedents of Patient Loyalty: Exploring Mediating and Moderating Paradigms in Public Hospitals. [PDF]
Hussain A+5 more
europepmc +1 more source
Efficiency Analysis of Public Hospitals Transformed into Public Corporations: An Application of Data Envelopment Analysis [PDF]
Sara Moreira
core
Public hospitals and health care reform: choices and challenges.
Dennis P. Andrulis+3 more
openalex +2 more sources
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou+11 more
wiley +1 more source
Effects of communication, trust, and respect on shared decision-making: insights from healthcare providers in Chinese public hospitals. [PDF]
Chen L+5 more
europepmc +1 more source
CRISPR/Cas9 screening reveals PTPN2 as essential for ALK+ ALCL survival. PTPN2 regulates TFRC to promote PINK1‐PRKN mitophagy. Oral PTPN2 inhibitor ABBV‐CLS‐484 disrupts mitochondrial renewal and blocks TFRC‐mediated mitophagy to exert anti‐tumor activities, supporting clinical development for ALK+ ALCL.
Wei‐Ting Wang+11 more
wiley +1 more source
Evaluation of the outpatient parenteral antimicrobial therapy (OPAT) service in Malaysian public hospitals: a mixed-methods study protocol. [PDF]
Lim AH+4 more
europepmc +1 more source