Results 71 to 80 of about 1,503,513 (311)

Analysis of hospital service areas in Istanbul [PDF]

After 1950's, the rapid expansion of Istanbul has created tremendous demand for new public facilities as well as the need for evaluation of existing facilities.
M. Aykut Sadi, Vedia Dokmeci
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Patient-Centered Care and Associated Factors among Adult Admitted Patients in South Wollo Public Hospitals, Northeast Ethiopia

Patient Preference and Adherence, 2022
Rahel G/egziabher,1 Gashaw Andargie Biks,2 Nigusu Worku,2 Bekalu Endalew,3 Endalkachew Dellie2 1Department of Public Health, College of Medicine and Health Sciences, Dilla University, Dilla, Ethiopia; 2Department of Health System and Policy, Institute of
G/egziabher R, Biks GA, Worku N, Endalew B, Dellie E   +4 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Public-private partnerships for hospitals

Bulletin of the World Health Organization, 2006
While some forms of public-private partnerships are a feature of hospital construction and operation in all countries with mixed economies, there is increasing interest in a model in which a public authority contracts with a private company to design ...
Martin McKee, Nigel Edwards, Rifat Atun
doaj  

Hospital length of stay and its predictors among surgical patients at public hospitals in Addis Ababa, Ethiopia

Frontiers in Surgery
BackgroundReducing the length of hospital stay can significantly lower healthcare costs, minimize the risk of hospital-acquired infections and complications, and improve patient well-being.
Samuel Dessu Sifer, Abduselam Ahmed Abdela, Milkiyas Solomon Getachew, Redait Awoke Assefa, Abatalem Minlargeh Abere   +4 more
doaj   +1 more source

The effects of upcoding, cream skimming and readmissions on the Italian hospitals efficiency: a population–based investigation [PDF]

In this paper we analyze the effects of some distortions induced by prospective payment system, i.e. Upcoding, Cream Skimming and Readmissions, on hospitals’ technical efficiency.
Berta, P, Callea, G, Martini, G, Vittadini, G   +3 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Experiences of Newly Qualified Registered Nurses (R.683) regarding negative workplace environment in selected hospitals of Limpopo Province, South Africa

SA Journal of Human Resource Management
Orientation: Globally, healthcare workplace environment is regarded as complex and interactive in nature, hence a supportive collegial environment is crucial in professional socialisation of newly qualified registered nurses, particularly (regulation ...
Tinyiko S. Baloyi, Dorah U. Ramathuba, Khathutshelo G. Netshisaulu   +2 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source