Results 71 to 80 of about 12,420,588 (261)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Annual report of the Massachusetts Memorial Hospitals

open access: yes, 1959
Annual report of the Massachusetts Memorial ...
Massachusetts Memorial Hospitals
core  

Hospital performance: costs of acute admitted patients in public hospitals in 2011–12 [PDF]

open access: yes, 2015
Some public hospitals spend nearly twice as much money as others to provide similar services to similar groups of patients. Overview Hospitals account for a large share of the funds Australia spends on the health sector each year. In 2011–12, about 30%
National Health Performance Authority
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Public-private partnerships for hospitals

open access: yesBulletin of the World Health Organization, 2006
While some forms of public-private partnerships are a feature of hospital construction and operation in all countries with mixed economies, there is increasing interest in a model in which a public authority contracts with a private company to design ...
Martin McKee, Nigel Edwards, Rifat Atun
doaj  

Addressing social responsibility of kidney healthcare facilities in Africa

open access: yesFrontiers in Health Services
Social responsibility (SR) in health is of paramount importance in the development of health systems. It is, therefore, frequently presented as one of the solutions for healthcare improvement in most developed countries.
Intissar Haddiya   +12 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Irish hospitals 1956-1971 [PDF]

open access: yes, 1971
This book details the Irish hospital activities funded by the Hospitals Trust Ltd (the Irish Hospital Sweepstakes) between 1956 and 1971, along with photographs of the hospitals ...
Hospitals' Trust (1940) Ltd
core  

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