Results 71 to 80 of about 678,029 (310)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Hospital governance and incentive design : the case of corporatized public hospitals in Lebanon [PDF]
There are three potential levels of government activity in the health sector: regulation, finance, and direct provision of services, with the government owning and managing hospitals and primary care clinics. Eid focuses on service provision.
Eid, Florence
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Do Hospitals Cross Subsidize? [PDF]
Cross-subsidies are often considered the principal mechanism through which hospitals provide unprofitable care. Yet, hospitals’ reliance on and extent of cross-subsidization are difficult to establish.
Guy David +3 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
American Women's Hospitals Service photographs: Yugoslavia - Skopje, undated
, 1917 The American Women's Hospitals (AWH) developed from the War Service Committee of the Medical Women's National Association (later, American Medical Women's Association (AMWA)) in 1917 to provide, register and finance American women physicians for war work;
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Australian hospital statistics 2012–13: private hospitals [PDF]
, 2014 Summary: In 2012-13, Australia\u27s 601 private hospitals accounted for 45% of the country\u27s 1,347 hospitals and 34% of all hospital beds. These private hospitals employed over 60,000 staff and had a total income of $11.8 billion.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Public-private partnerships for hospitals
Bulletin of the World Health Organization, 2006 While some forms of public-private partnerships are a feature of hospital construction and operation in all countries with mixed economies, there is increasing interest in a model in which a public authority contracts with a private company to design ...
Martin McKee, Nigel Edwards, Rifat Atun
doaj
American Women's Hospitals Service photographs: Individual portraits of personnel, undated
, 1917 The American Women's Hospitals (AWH) developed from the War Service Committee of the Medical Women's National Association (later, American Medical Women's Association (AMWA)) in 1917 to provide, register and finance American women physicians for war work;
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