Results 131 to 140 of about 277,535 (306)

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu   +10 more
wiley   +1 more source

English Housing Survey, 2021: Housing Stock Data [PDF]

open access: yes
copyright UK Data Service and data collection copyright owner.The English Housing Survey (EHS) is a continuous national survey commissioned by the Ministry of Housing, Community and Local Government (MHCLG) that collects information about people's ...
Ministry of Housing, Communities and Local Government
core  

National Social Housing Survey: detailed results 2012 [PDF]

open access: yes, 2013
The 2012 National Social Housing Survey (NSHS) is the most recent in a series of surveys of social housing tenants and their experiences. The 2012 NSHS sampled tenants of public housing (PH); state owned and managed Indigenous housing (SOMIH) and ...

core  

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

English Housing Survey, 2022: Housing Stock Data [PDF]

open access: yes
copyright UK Data Service and data collection copyright owner.The English Housing Survey (EHS) is a continuous national survey commissioned by the Ministry of Housing, Community and Local Government (MHCLG) that collects information about people's ...
Ministry of Housing, Communities and Local Government
core  

The health, employment and education benefits of public housing [PDF]

open access: yes, 2005
The reduced housing costs, increased residential stability, reduced crowding and more socially diverse neighbourhoods provided to new public tenants benefit educational outcomes for children, the health and well being of tenants, and reduce health costs ...
Young, Peter, Phibbs, Peter
core  

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

open access: yesAdvanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao   +12 more
wiley   +1 more source

Public hearing : Governor's Commission on Housing and Homelessness, August 17, 1993 at 8:00 a.m., Statehouse, Topeka [1993] [PDF]

open access: yes, 1993
Public Hearing Governor's Commission On Housing & Homelessness August 17, 1993 At 8:00 A. M. Statehouse, Topeka -- Grants/Clearinghouse -- Mary Lundin, Mayor of Mayetta -- Rosemary Harris, Older Citizen's Information -- Joe Eaton, Kansas Banker's ...
Kansas Governor's Commission on Housing and Homelessness
core  

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

Home - About - Disclaimer - Privacy