Results 21 to 30 of about 203,402 (218)

ANALISIS GENANGAN BANJIR AKIBAT LUAPAN BENGAWAN SOLO UNTUK MENDUKUNG PETA RISIKO BENCANA BANJIR DI KABUPATEN BOJONEGORO

open access: yesJurnal Teknik Pengairan, 2017
ABSTRAK: Jumlah kejadian banjir di kabupaten Bojonegoro sebanyak 105 kejadian dari kurun waktu 1815 sampai dengan 2016 (BNPB, 2016). Kejadian banjir di Bojonegoro umumnya diakibatkan oleh luapan Bengawan Solo.
Asep Sulaeman   +2 more
doaj   +1 more source

Spatial Multi-Criteria Analysis and Least-Cost Path on The Highway Route Planning: A Case Study of Bawen – Yogyakarta Highway, Indonesia

open access: yesGeoplanning: Journal of Geomatics and Planning, 2020
Infrastructure planning ideally not only considers the geotechnical aspects and physical conditions of the infrastructure development location but also must be able to support regional development.
Bramantiyo Marjuki, Iwan Rudiarto
doaj   +1 more source

Reinforced Concrete Corbel’s Behavior using Strut and Tie Model

open access: yesJournal of the Civil Engineering Forum, 2018
Reinforced concrete (RC) corbel is one of a disturbed region of elements of the structure. SNI 2847: 2013 as a guideline from Ministry of Public Works provides the design of RC corbels by the conventional method and with Strut and Tie Model (STM).
Mutmainnah Rahman Putri
doaj   +1 more source

The Prediction of Debris Flow Based on Eruption and Rainfall Event for River Infrastructure Mitigation: Study Case Opak River, Sleman Regency [PDF]

open access: yesE3S Web of Conferences
Mount Merapi is a volcano active in Indonesia. The eruption that occurred in 2010 was a major eruption with a return period of 100 years. Dominant debris to the Opak – Gendol Watershed; the biggest debris flood occurred in 2010 – 2011.
Hadiranti   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Keureuto Dam Operation for Flood Control System [PDF]

open access: yesE3S Web of Conferences
Floods are one of the most destructive natural disasters. Dams are engineered structures built across rivers and streams to control water flow, primarily for purposes like water supply, hydroelectric power generation, and flood control. In the modern era,
Variadi Variadi   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

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