Results 41 to 50 of about 22,684,611 (251)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Exploring cultural image of Souq Putrajaya public realm

open access: yes, 2022
This study discusses on the issues of successes and weaknesses aspects of cultural image in the bazaars public realm in Putrajaya city. The poor quality and the lack of the local cultural image in the bazaars public realm in Putrajaya has reduced the ...
Mohd Yunos, Mohd Yazid   +2 more
core   +1 more source

Working Order: Health, Personal Responsibility, and Rights in an Age of Limited Agency

open access: yesChristian Journal for Global Health, 2019
A seeming contradiction exists between the approach to health as a fundamental human right or as the natural consequence of human responsibility. This paper investigates a Christian approach to health attempting to reconcile these disparate views.
Mark Crouch
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Nurses' Self Perception about their Public Image in a Metropolitan City, Karachi

open access: yesJournal of the Dow University of Health Sciences, 2016
Objective: The purpose of the study was to explore and describe the diploma- prepared nurses' self-perception about their public image in a metropolitan city of Karachi, Pakistan.
Sarfaraz Masih, Laila Gulzar
doaj   +2 more sources

APPLICATION OF NANOBIOMATERIALS IN RESTORATIVE DENTISTRY [PDF]

open access: yesJournal of IMAB, 2016
Nanodentistry is defined as the science and technology of diagnosing, treating and preventing oral and dental diseases, relieving pain, preserving and improving dental health using nanostructured material.
Maya Lyapina   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Iron lady, reflexiones sobre la imagen y el liderazgo. Iron lady, reflections about image and leadership

open access: yesFotocinema: Revista Científica de Cine y Fotografía, 2012
A través de diversas teorías sobre el liderazgo así como la influencia del cine en el legado visual y biográfico de algunas personalidades relevantes, este artículo analiza el liderazgo de Margaret Thatcher mostrado en la película Iron Lady, sobrenombre ...
María Arnal Canudo
doaj  

General perception of the diversification of child-rearing environments in Japan

open access: yesFrontiers in Sociology
Understanding how child-rearing environments and family dynamics evolve in response to socioeconomic change and shifting cultural values is a central question in sociology.
Kazushi Maruya   +4 more
doaj   +1 more source

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