Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Institutional Theories and Public Institutions: Traditions and Appropriateness [PDF]
Public institutions are organized configurations which are prone to institutionalization processes. They reflect as well as produce and diffuse valuues, norms, cognitions, meanings and identities about life and evolution of society, polity or economy.
openaire +2 more sources
Institutions and Practices for Restoring and Maintaining Public Order [PDF]
In the wake of the atrocities committed in Cambodia, southern Sudan, the former Yugoslavia, Rwanda and Haiti, many in the international community have called for the creation of ad hoc or standing international criminal courts to deal with some types of ...
Reisman, W. Michael
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
This investigation elucidates the genetic connection between major depressive disorder (MDD) and metabolic syndrome (MetS), suggesting bidirectional genetic correlations and shared pleiotropic genes.
Yiheng Feng +6 more
doaj +1 more source
Factors affecting the public judgement of consumer protection authorities [PDF]
The article first introduces the state-provided institutions for consumer protection in Hungary, then examines and systematises those factors having a significant impact on the public judgement of the work of consumer protection authorities. The study is
Csiszár, Csilla Margit
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
CCR4⁺ memory Tregs and PD-1⁺ T cells as novel immunodiagnostic biomarkers for active tuberculosis
Background Tuberculosis (TB), caused by Mycobacterium tuberculosis(M.tb), remains a major global infectious disease. T cell-mediated immune responses play a crucial role in host defense against TB.
Qiang Zhang +9 more
doaj +1 more source
Corruption and quality of public institutions: evidence from Generalized Method of Moment [PDF]
The aim of this paper was to re-examine the relationship between the quality of public institutions and corruption. Estimations from generalized method of moments show that better public institutions (regulation, bureaucracy, political structures) are ...
Gbewopo Attila
core +3 more sources
Factors Affecting Public Engagement by Researchers: a Study on Behalf of a Consortium of Uk Public Research Funders [PDF]
The "Factors affecting public engagement by researchers" project suggests that the embedding of public engagement in institutional cultures is best understood as a 'work in progress'.
Becky Hamlyn +4 more
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