Results 31 to 40 of about 199,366 (264)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Regional Disparities and Fiscal Policy Challenges in Romania's Economic Growth Trajectory [PDF]

Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics
This paper investigates the relationship between fiscal policy and regional economic growth disparities in Romania, a country characterized by persistent territorial imbalances.
Daniel Stadoleanu, Mihaela Neculita
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

What works to prevent violence against women, domestic abuse and sexual violence (VAWDASV)? A systematic evidence assessment

Journal of Community Safety and Well-Being, 2023
This review identifies effective practice for the prevention of violence against women, domestic abuse and sexual violence (VAWDASV). The review is underpinned by public health principles which provide a useful framework to understand the causes and ...
Samia Addis, Lara Snowdon
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Dvelopment and application of similar material for physical model test of an ultradeep foundation pit in round gravel strata

Scientific Reports
The raw-material mix ratio and preparation of similar materials are crucial for the success of physical model tests and for accurately reflecting prototype properties.
Yanhui Guo, Xipeng Ren, Shaoqian Liu, Xiaobing Fu, Guo Yuan, Guoyang Zhang, Yi Yang, Zhiquan Yang, Xiangyu Wang, Ming Ni   +9 more
doaj   +1 more source

Command-driven vs. market-oriented environmental regulations: impacts on high-quality development of manufacturing industry

Frontiers in Environmental Science
The manufacturing industry is a key area of environmental regulation. However, whether command-driven and market-oriented environmental regulations exert heterogeneous impacts on the high-quality development of the manufacturing industry (HQDM) remains ...
Chunxin Lin, Keqiang Wang, Hongmei Liu
doaj   +1 more source

Bias‐Triggered Conductivity Relaxation (BCR): A Unique Tool to Simultaneously Investigate Thermodynamics, Kinetics, and Electrostatic Effects of Oxygen Reactions in MIEC Thin Films

Advanced Materials, EarlyView.
This work develops bias‐triggered conductivity relaxation as a novel technique to study oxygen reactions in mixed ionic‐electronic conducting thin films by integrating electrochemical titration and electrical conductivity relaxation to achieve synchronous multi‐parameter characterization, providing simultaneous electronic, ionic, and extraordinarily ...
Alexander Stangl, Alexander Schmid, Adeel Riaz, Jürgen Fleig, Arnaud Badel   +4 more
wiley   +1 more source

Intelligent Sky Guardians (InSkyGuard): An Aerial Robotic Swarm for Autonomous Detection and Entrapment of Rogue Multirotors

Advanced Robotics Research, EarlyView.
Intelligent Sky Guardians (InSkyGuard) is introduced as a four‐drone swarm that autonomously detects, tracks, and safely captures rogue drones using a coordinated net system. Computer vision and leader–follower control architecture enable synchronized enclosure, while integrated failsafes enhance system reliability. Validated through closed‐environment
Joshua Hastings, Levanya Dewanarayana, Iline Shaju, Haider Al‐Wizni, Sampson Marquis, Weicheng Huang, Pooya Sareh   +6 more
wiley   +1 more source