Results 41 to 50 of about 4,345,687 (360)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Mediating punitiveness: understanding public attitudes towards work-related fatality cases [PDF]

open access: yes, 2010
This paper concerns an empirical investigation into public attitudes towards work-related fatality cases, where organizational offenders cause the death of workers or members of the public.
Eser A.   +18 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Advancing the Right to Health: The Vital Role of Law [PDF]

open access: yes, 2017
Effective laws and an enabling legal environment are essential to a healthy society. Most public health challenges – from infectious and non-communicable diseases to injuries, from mental illness to universal health coverage – have a legal component.
Cabrera, Oscar A.   +4 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

(Private & Public Law) ( Attempts between cancelation and resistance ) [PDF]

open access: yesمجلة الاجتهاد للدراسات القانونية والاقتصادية, 2019
It was settled in the jurisprudence mind that the law divided in to two section, private law and public law. And each of these sections collect some kinds of rules. This dividing depends on some criteria such as the public interest and the personality of
Amira almardhi awad
doaj  

Contemporary Human Rights and Offensive Jihad in Contemporary Islam [PDF]

open access: yesپژوهش‌نامه حقوق اسلامی, 2011
Offensive Jihad as one of the branches of the holy religion of Islam is so significant that one particular chapter is devoted to this issue in jurisprudential sources. Offensive Jihad is a two-fold regulation raising questions in two ways.
Mohammad javad javid, Ali mohammad dost
doaj   +1 more source

Mental health service use among mothers involved in public family law proceedings: linked data cohort study in South London 2007–2019 [PDF]

open access: hybrid, 2022
Rachel Pearson   +6 more
openalex   +1 more source

Open Meetings: Land Use Mediation and the Public\u27s Right to Know [PDF]

open access: yes, 2003
Great uncertainty surrounds the New York Open Meetings Law (OML), a law that permits the public to attend meetings of public bodies. Obviously, the OML becomes especially crucial in the area of land use where public governmental meetings are the norm ...
Nolon, John R.
core   +1 more source

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