Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Comment on "Can Public Managers Learn from Trends in Manufacturing Management?"
The article is well done but several critical comments occur to me related more to the premise on which it is based than the execution of the theme.
Mizaur, Donald
core
Being bound and tied by the ropes of frugality: a case study on public management values and service integration. [PDF]
Løken TD +3 more
europepmc +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
The public policies evaluation, despite not being a recent theme its importance has been increasing and stimulated by society’s demands for the public policies universalization and the citizenship realization.
Regina Claudia Laisner +1 more
doaj
In Between New Public Management and Network Governance in Austria, Finland and Scotland: Potential Conflicts in Autonomy Understandings of Governments and Universities. [PDF]
Stransky-Can K.
europepmc +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
The Urban Green Space Index (UGSI) is an indicator that measures the quantity, quality, accessibility, and distribution of green spaces in urban environments.
Andrea Damaris Hernández-Allauca +7 more
doaj +1 more source
How Can Science and Research Work Well? Toward a Critique of New Public Management Practices in Academia From a Socio-Philosophical Perspective. [PDF]
Kruse JP.
europepmc +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source

