Results 111 to 120 of about 11,473,731 (348)

Apológia: A közszolgálatiság szerepvállalása a későmodern média korában

open access: yesSymbolon, 2015
Apology: The Role of Public Media in the Era of Late Modern Media In our presentation, we give an outline of the aspect public service aims to assume in the present era of late modern media in terms of involvement and contents.
Attila Csaba Gáspárik   +1 more
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Universal Access? Investigating News Deserts in the American Public Media System

open access: yesInternational Journal of Communication
In recent years, scholars, journalists, and policymakers have suggested a robust public media system as a possible solution to the growing local news deserts in the United States.
Louisa Lincoln
doaj   +2 more sources

Digital media in public archaeology [PDF]

open access: yes, 2017
The twenty years following the mid-1990s witnessed a step change in the communication landscape, which can be summarised under the label of new digital media. In this period, the popularity of the Internet and mobile technologies has become more widespread, and previously distinct media forms have been progressively converging into fewer and ‘newer ...
openaire   +3 more sources

Mass media: constrained information and heterogenous public

open access: yes, 2006
This paper investigates how mass medium (sender) provides information to readers or viewers (receivers) who have diverse interests. The problem of the sender comes from the fact that there is a constraint on how much information can be delivered.It is ...
Kwiek, Maksymilian
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

180 years of marine animal diversity as perceived by public media in southern Brazil. [PDF]

open access: yesPLoS One, 2023
Herbst DF   +5 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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