Results 81 to 90 of about 798,503 (269)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Spišský Hrhov as an example of the complexity of relations between Roma and non-Roma on the local level [PDF]

open access: yesAnnales Scientia Politica, 2018
The paper focuses on the presentation and analysis of activities aimed at improving the situation of the Romani community in Spišský Hrhov. We point out and explain that the conditions faced by local Roma cannot be perceived as ideal; that the whole ...
Alexander Mušinka
doaj  

Digital media in public archaeology [PDF]

open access: yes, 2017
The twenty years following the mid-1990s witnessed a step change in the communication landscape, which can be summarised under the label of new digital media. In this period, the popularity of the Internet and mobile technologies has become more widespread, and previously distinct media forms have been progressively converging into fewer and ‘newer ...
openaire   +3 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Women as mayors: the political representation of women in the leadership of Slovak municipalities after the municipal elections in the year 2010 [PDF]

open access: yesAnnales Scientia Politica, 2018
The paper analyses women’s representation at the local level in Slovakia, or at the level of all (almost three thousand) Slovak municipalities, respectively.
Pave Maškarinec
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Permeability of the Slovak ‒ Ukrainian border [PDF]

open access: yesAnnales Scientia Politica, 2018
In this paper, we examine the permeability of the border between the Slovak Republic and Ukraine. On the basis of data from the Office of the Border and Alien Police of the Ministry of Interior of the Slovak Republic we analyse the development of legal ...
Helena Melkusová
doaj  

Institute of Political Science as part of the International Visegrad Fund project (report) [PDF]

open access: yesAnnales Scientia Politica, 2020
International conference ...
Gabriel Székely
doaj  

Public relations of the public service media [PDF]

open access: yesKultura, 2013
Funds available to public service broadcasters have shrunk all across Europe and the world economic crisis is not the single reason behind this. PSM (Public Service Media) have lost a good portion of public support and there lies the second most important reason. There are fewer opportunities to preserve this sort of the media in contemporary societies,
openaire   +1 more source

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