Results 91 to 100 of about 7,686,922 (303)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The Problem of State Sovereignty in the Modern Geopolitical Conditions

open access: yesУправленческое консультирование, 2018
The transformation of state sovereignty in the twenty-first century became a real challenge to the international system. Some countries ceased to exist fully independently from the surrounding world economy and universal communication system.
Viktor Petrovich Kirilenko   +1 more
doaj  

Limitations of freedom of ownership and testamentary freedom [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2019
The first issue discussed in this paper relates to freedom of ownership, which is perceived as a part of the general freedom of individual, which limitations are presented through numerous theoretical classifications, conditioned by positive law and ...
Đurđić-Milošević Tamara V.
doaj  

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

(On) the reasons for invalidity of wills in Serbian and comparative law [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu
: In order to be legally valid, a will, as a legal act mortis causa, must fulfill certain conditions as prescribed by each specific legal system.
Vidić Jelena Đ., Kovačević Milica S.
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Social Media, Violence and the Law: ’Objectionable Material’ and the Changing Countours of Hate Speech Regulation in India

open access: yesCulture Unbound: Journal of Current Cultural Research, 2019
With the advent of the internet and increasing circulation of hate speech, and material that has been linked to public order disturbances, there has been a shift in the legal discourse around hate speech.
Siddharth Narrain
doaj  

INTERNET AND PUBLIC ORDER

open access: yes, 2018
If we accept, as we should, that the use of the Internet is related to the recognition of several constitutional rights and liberties (right of expression, communication, publication, advertisement, and so on), we are then obliged to search for the legitimate regulatory institution in this domain.
openaire   +2 more sources

REFORMING THE PUBLIC ADMINISTRATION THROUGH E-GOVERNMENT GENERALIZATION [PDF]

open access: yes
The paper outlines the role of e-government as the main action in order to reform Romanian public services. E-government is a critical constituent of the new information and knowledge-based society and in the last few years had an exponential evolution ...
Andreea ZAMFIR
core  

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