Results 281 to 290 of about 1,645,598 (358)
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo +5 more
wiley +1 more source
Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu +12 more
wiley +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Spatiotemporal trends and determinants of syphilis among heterosexual males and females in the Netherlands, 2011 to 2023. [PDF]
Kayaert L +3 more
europepmc +1 more source
Intimate partner violence experience, support seeking and coping strategies among pregnant women in Southwestern Uganda. [PDF]
Katushabe E +6 more
europepmc +1 more source
Prevalence of Severe Thalassemia and Performance of Prenatal Screening Tests Among Pregnant Women at Siriraj Thalassemia Center in Thailand. [PDF]
Malasai K +6 more
europepmc +1 more source
Sexual Behavior, App Use, and Venue Comfort During COVID-19: A Global Study of Gay, Bisexual, and Other Men Who Have Sex with Men. [PDF]
Jauregui JC +4 more
europepmc +1 more source

