Results 41 to 50 of about 1,645,598 (358)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Prioritizing syphilis control: Now is the time for action

open access: yesFrontiers in Medicine, 2022
Syphilis control programs and research received fewer resources and attention compared to HIV and other sexually transmitted infections (STIs) in the pre-pandemic era.
Joseph D. Tucker   +8 more
doaj   +1 more source

Intimate Partner Violence and Sexual Violence in the Municipality of Anchorage: Key Results from the 2011 Alaska Victimization Survey [PDF]

open access: yes, 2011
This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the Municipality of Anchorage, which was conducted from April to June 2011, with results released on October 3, 2011 in Anchorage. Findings include: *
Rosay, André B.
core  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in the Kodiak Island Borough: Key Results from the 2012 Alaska Victimization Survey [PDF]

open access: yes, 2012
This document is a two-page summary of the key results from the 2012 Alaska Victimization Survey for the Kodiak Island Borough, which was conducted from March to May 2012, with results released on October 4, 2012 in Kodiak.
Rosay, André B.
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

‘Get away from it all’ or ‘Too good to be true?’: a qualitative exploration of job advertisements for remote and rural posts

open access: yesRural and Remote Health
Introduction: Recruitment and retention of the healthcare workforce are crucial to maintaining access to services and provision of care, but these are ongoing challenges for health services both in the UK National Health Service (NHS) and globally.
Zoë Skea   +12 more
doaj   +1 more source

Intimate Partner Violence and Sexual Violence in the City and Borough of Sitka: Key Results from the 2012 Alaska Victimization Survey [PDF]

open access: yes, 2012
This document is a two-page summary of the key results from the 2012 Alaska Victimization Survey for the City and Borough of Sitka, which was conducted from March to May 2012, with results released on October 19, 2012 in Sitka. Findings include: * 47%
Rosay, André B.
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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