Results 81 to 90 of about 1,645,598 (358)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Federal Benefits and the Same-Sex Partners of Federal Employees [PDF]

open access: yes, 2012
[Excerpt] This report examines current policies on the application of benefits to the same-sex partners of federal employees and reviews certain policy debates about the extension or removal of these benefits.
Ginsberg, Wendy, Topoleski, John J
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Advantages, disadvantages and risks of public-private partnership

open access: yesRUDN Journal of Law, 2012
The article investigates the advantages, disadvantages and risks of public-private partnership. Investigated the risks for the public partner and for the private partner.
V E Sazonov
doaj  

OSOBOWE SPÓŁKI JEDNOOSOBOWE

open access: yesZeszyty Prawnicze, 2016
Single – Partner Partnership Summary The Commercial Companies Code contains regulating of a single – member private limited-liability company and a single – member public company, but partnership can also have single partner. It can not be incorporate
Tomasz Szczurowski
doaj   +1 more source

Academic-Community Partnerships: Effectiveness Evaluated Beyond the Ivory Walls [PDF]

open access: yes, 2019
Community-based participatory research (CBPR) has furthered our understanding of the working principles required for academic-community partnerships to address persistent public health problems.
Caron, Rosemary M.   +2 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

High rate of partner violence during pregnancy in eastern Ethiopia: Findings from a facility-based study.

open access: yesPLoS ONE, 2020
INTRODUCTION:Intimate partner violence during pregnancy can contribute to maternal mortality and morbidity by limiting women's ability to receive maternal health services including antenatal care and skilled delivery care. In Ethiopia, evidence regarding
Abdulbasit Musa   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy