Results 121 to 130 of about 3,403,124 (306)

Variability of human behaviour in outdoor public spaces, associated with the thermal environment [PDF]

open access: yes, 2017
This paper presents part of the outcomes of a programme of research into the influence of the thermal environment on human behaviour in an outdoor public seating area.
Cobb, Sue   +3 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Public Bicycles: How the Concept of Human-Oriented “Mobility Sharing” Technology Can Influence Travel Behaviour Norms and Reshape Design Education [PDF]

open access: yes
Although at the moment an excess of 500 public bicycle schemes of variable sizes operate in almost 50 countries worldwide, the impact of their use on travel behaviour and modal change have neither been studied extensively nor have been understood ...
Nikitas, Alexandros   +2 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Reference-dependent preferences in the public and private sectors: A nonlinear perspective [PDF]

open access: yes
Although existing studies in the strategic management literature examine the importance of reference points in the context of managerial decisions vis-à-vis organizational performance, there is surprisingly little evidence on how reference earnings ...
Georgellis, Yannis   +2 more
core   +1 more source

Prayer room design in transit area [PDF]

open access: yes, 2015
The prayer room in transit area such as shopping mall, an exhibition hall,an airport,or other public building is an intervention to its surrounding and a welcoming place to find shelter or stop briefly, as a place of transit in our routine life.
Daud, Lutfi   +7 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Exploring the Impact of Accessibility on Place Attachment in Urban Public Open Spaces: A Case Study of Jiamusi City, China

open access: yesBuildings
Urban public open spaces are crucial for residents’ well-being, yet accessibility issues persist, affecting activities and social interactions. To this end, we take the main urban area of Jiamusi City, the most northeastern city in China, as an example ...
Jun Zhang, Zixuan Zhang, Yimeng Liang
doaj   +1 more source

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