Results 121 to 130 of about 592,392 (268)

Leading the Pack: Next‐Generation Batteries for Humanoid Robotics

Advanced Science, EarlyView.
Humanoid robots challenge traditional and anticipated energy technologies. Humanoid robot benchmarks of runtimes and energy demands for industry applications inform humanoid robot battery design choices at the cell level, pack level, and system level.
Matthew Bergschneider, Jiaqi Ke, Jin Luo, Laisuo Su, Thomas Campbell, Yue Zhou, Kyeongjae Cho   +6 more
wiley   +1 more source

PrEP public policies for HIV prevention in South America: an intersectional analysis. [PDF]

BMC Public Health
de Oliveira KH, de Oliveira Ferreira B, da Silva Junior FJ, Barp LFG, de Menezes Guerra CB, da Silva Câmara FD, de Almeida Soares MA, Bercht G, Honorato IB, Gagliolo AA, García MG, Dos Reis RP, Passamani GR, Kauss BS, Vallejo FR, Hurtado JCA, das Neves ALM.   +16 more
europepmc   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Public policies and their association with adolescent pregnancy in Southern Peru. [PDF]

Reprod Health
Medrano-Sánchez EJ, Alanya-Pereyra LL, Ochoa-Tataje F.   +2 more
europepmc   +1 more source

Public policies strengthen the relationship between family farming and food security in Brazilian schools - A case study of Paraíba state. [PDF]

Heliyon, 2023
Martinez P, de Lourdes Saturnino Gomes M, Marini FS.   +2 more
europepmc   +1 more source

Trustworthy Multimodal Attention Framework for Creep Rupture Life Prediction Under Data‐Scarce Conditions: A Case Study on IN718

Advanced Science, EarlyView.
An attention‐based multimodal deep learning framework is developed to predict the creep life of Ni‐based superalloys by fusing processing parameters with microstructural micrographs. The model achieves high accuracy (R2 = 0.92), aligns with metallurgical principles by capturing δ‐phase influence, and incorporates uncertainty quantification, offering a ...
Haopeng Lv, Dayong Wu, Ziyuan Rao, Qian Wang, Haikun Ma, Jie Kang, Wang Li, Huicong Dong, Yandong Wang, Zhinan Yang, Ru Su   +10 more
wiley   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Declaration of Santo Domingo: commitment to improve education, regulations, public policies, and access to peritoneal dialysis in Latin America. [PDF]

J Bras Nefrol
Moretta-Pedernera GL, Ramos-Sánchez A, Cortés-Sanabria L, Chaúd-Covarrubias R, Álvarez-Estévez G, Uribe M, Sánchez-Polo V, Divino-Filho JC, Wasmuth-Troche NM, Batista-Buitrago L, Avellán-Boza M, Orozco-Bass R, Martínez-Eusebio H, Soto-Velásquez R, Papaginovic-Leiva MM, Gómez-Luján M, Rodríguez-Manzano S, Rodríguez-Chagolla JM, Molina-Comboni DA, Álvarez-González Y, Crespo PJD, Campos EI, Moura-Neto JA, Hinojosa M, Vásquez-Jiménez LC, García-Villalobos GG, González G, Dina-Batle E, Álvarez-Novoa JR.   +28 more
europepmc   +1 more source

Mathematical Modeling for the Assessment of Public Policies in the Cancer Health-Care System Implemented for the Colombian Case. [PDF]

Int J Environ Res Public Health, 2023
Rojas-Díaz D, Puerta-Yepes ME, Medina-Gaspar D, Botero JA, Rodríguez A, Rojas N.   +5 more
europepmc   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

Advanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li, Jun‐Ze Jiang, Ying‐Ying Liu, Tian‐Tian Zhang, Kanwar Kumar Malhi, Xin Yao, Jin‐Long Li   +6 more
wiley   +1 more source