Results 41 to 50 of about 3,736,736 (315)

Barriers and Facilitators in Pricing and Funding Policies of European Countries That Impact the Use of Point-of-Care Diagnostics for Acute Respiratory Tract Infections in Outpatient Practices

Diagnostics, 2023
Antimicrobial resistance is a major global health threat, which is increased by the irrational use of antibiotics, for example, in the treatment of respiratory tract infections in community care.
Caroline Steigenberger, Friederike Windisch, Sabine Vogler   +2 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Modeling the circular economy in food production: insights from a dynamic stochastic general equilibrium analysis

Scientific African
This study explores the impact of circular economy practices on the sustainability and productivity of the food sector through a Dynamic Stochastic General Equilibrium (DSGE) model.
Abdelhamid Moustabchir, Hicham Ouakil, Hicham EL Ouazzani   +2 more
doaj   +1 more source

The effects of austerity measures on quality of healthcare services: a national survey of physicians in the public and private sectors in Portugal

Human Resources for Health, 2017
Background The European Union member countries reacted differently to the 2008 economic and financial crisis. However, few countries have monitored the outcomes of their policy responses, and there is therefore little evidence as to whether or not ...
Tiago Correia, Graça Carapinheiro, Helena Carvalho, José Manuel Silva, Gilles Dussault   +4 more
doaj   +1 more source

Law-Based Arguments and Messages to Advocate for Later School Start Time Policies in the United States [PDF]

, 2017
The increasing scientific evidence that early school start times are harmful to the health and safety of teenagers has generated much recent debate about changing school start times policies for adolescent students.
Lee, Clark J, Lockley, Steven W, Nolan, Dennis M, Pattison, Brent   +3 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Urban Compactivity Models: Screening City Trends for the Urgency of Social and Environmental Sustainability

Urban Science, 2021
Urban compactivity models are increasing around the globe, and sustainability has become the new buzzword. In recent decades, the focus of ecological responsibility has been shifted to the world’s cities, as they are the source of excessive consumption ...
Nadine Lobner, Paulo Castro Seixas, Ricardo Cunha Dias, Diogo Guedes Vidal   +3 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Application of Big Data to Support Evidence-Based Public Health Policy Decision-Making for Hearing [PDF]

, 2020
Ideally, public health policies are formulated from scientific data; however, policy-specific data are often unavailable. Big data can generate ecologically-valid, high-quality scientific evidence, and therefore has the potential to change how public ...
Andermann, Barker, Basu, Benke, Choi, Christensen, Deiner, Dritsakis, Ferguson, Gatehouse, Greer, Gutenberg, Hernandez, Horsman, Howell, Katrakazas, Kehler, Konstantopoulos, Larsen, Lee, Livingston, Luo, Mahmoudi, Mellor, Michopoulos, Mooney, Moyer, Murdoch, Nasreddine, Obermeyer, Oliver, Orton, Polanczyk, Raghupathi, Reavis, Salathé, Schilder, Shardell, Shiffrin, Topol, Tu, Ullah, van de Goor, Vos, Willink, Yaffe, Young, Zigmond   +47 more
core   +3 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source