Results 281 to 290 of about 5,139,772 (404)

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

open access: yesCancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li   +23 more
wiley   +1 more source

Treatment outcomes and costs of a simplified antiretroviral treatment strategy for hepatitis C among Hepatitis C Virus and Human Immuno deficiency Virus co‐infected patients in Ukraine

open access: yesJGH Open, Volume 6, Issue 12, Page 894-903, December 2022., 2022
We assessed treatment and cost outcomes for integrated HIV and viral hepatitis testing with ledipasvir/sofosbuvir ± weight‐based ribavirin for 12 weeks in Kyiv, Ukraine. Overall, a sustained virological response (SVR) was achieved in 831 of 868 patients (95.7%).
Sergie Antoniak   +24 more
wiley   +1 more source

Competition in Public Procurement in the Czech and Slovak Public Health Care Sectors. [PDF]

open access: yesHealthcare (Basel), 2020
Nemec J   +3 more
europepmc   +1 more source

Do procurement rules impact infrastructure investment efficiency ? an empirical analysis of inversao das fases in Sao Paulo state [PDF]

open access: yes
As a means to reduce delays in public works implementation, a number of Brazilian states have recently reformed their procurement rules allowing contractor price proposals to be assessed before the technical evaluation of submitted bids is undertaken (in
Blancas, Luis   +4 more
core  

Enabling modernisation, marginalising alternatives? Kenya's agricultural policy and smallholders

open access: yesJournal of International Development, Volume 35, Issue 1, Page 3-20, January 2023., 2023
Abstract To address intensifying social and environmental challenges, development policy must learn from inclusions and exclusions of past discourses. We analyse Kenya's post‐colonial agricultural policy discourse. Our analysis reveals a near‐exclusive focus on the promotion of agricultural modernisation based on industrial farm inputs, a bureaucratic ...
Fredrick Ajwang   +4 more
wiley   +1 more source

Building Political Collusion: Evidence from Procurement Auctions [PDF]

open access: yes
We investigate the relationship between the time politicians stay in office and the functioning of public procurement. To this purpose, we collect a data set on the Italian municipal governments and all the procurement auctions they administered between ...
Coviello, Decio, Gagliarducci, Stefano
core  

Tackling Environmental Impact: A New Support Tool for Sustainable Healthcare Waste Management

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study proposes a novel framework integrating Environmental Risk Assessment (ERA) and Material Flow Analysis (MFA) within the Deming Cycle framework to address this gap. While valuable tools, ERA and MFA offer limited perspectives on environmental impact when used alone.
Carlotta D'Alessandro   +4 more
wiley   +1 more source

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