Results 101 to 110 of about 2,740,550 (314)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Alaska Trial Court Caseload FY 2007–2018 [PDF]
Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on criminal case filings in Alaska trial courts for fiscal years 2007–2018.
Kisarauskas, Yevgenii
core
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Property Taxation in the People\u27s Republic of China [PDF]
A property tax is a general tax imposed on all property owners based on the value of their properties. Property taxation is common throughout the world due to its numerous advantages. It is regarded as a steady source of local government revenue.
Asian Development Bank
core +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Capitalization of the Public Domain. Public Concession Contract
The field of public acquisition has a special relevance whose core consists in the involvement of public capital for their realization. Public acquisition enjoys an importance both at national and European level, being a stage that precedes and ...
Maria-Cristiana Ieremie
doaj
REVISITING COMMONS – ARE COMMON PROPERTY REGIMES IRRATIONAL? [PDF]
This paper revisits the debate about communal management of natural resources and brings together various issues confronting it. Much of the criticism against common property regimes stems from an incorrect modeling of a common property situation, and ...
Hasan, Lubna
core +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Comparing safety climate in infrastructure and building projects in Indonesia
Despite the rapid growth of the Indonesian construction industry and its significance to the national economy, health and safety in the industry remains poor.
Sunindijo Riza Yosia +6 more
doaj +1 more source

