Results 51 to 60 of about 2,724,752 (315)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Rental of Public Property Assets
EIRP Proceedings, 2020 In this article, using the logical interpretation, the jurisprudence study, but also the comparative analysis, we have proposed to analyze the rental of public property assets from the perspective of the provisions of the Administrative Code.
Vasilica Negruț
doaj
Welfarism in economic domains [PDF]
, 2000 In economies with public goods, and agents with quasi-linear preferences, we give a characterization of the welfare egalitarian correspondence in terms of three axioms: Pareto optimality, symmetry, and solidarity.
Ginés, Miguel, Marhuenda, Francisco
core +3 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Foreword: The Opposite of Property? [PDF]
, 2003 In November of 2001, Duke University School of Law held a conference on the public domain; the outside of the intellectual property system, the material that is free for all to use and to build upon.1 So far as we could tell, this was the first ...
Boyle, James
core +1 more source
The United States Claims Court: A Safe Harbor from Government Regulation of Privately Owned Wetlands [PDF]
, 1992 Efforts to protect wetlands under the Federal Clean Water Act and State Environmental Laws have led to an increasing number of actions in the U.S. Court of Claims brought by landowners for just compensation due to a taking of their property through ...
Kennedy, Patrick
core +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Challenges in implementing the public property regulations in Serbia [PDF]
Zbornik Radova Pravnog Fakulteta u NišuThe effectiveness of the disposal of public property in a country is conditioned by several factors: the legal framework and its application, the availability of information and documents on the disposal of public property, and the responsibility of the ...
Nikolić Ljubica
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Plant Direct, 2020 The constitutively active missense allele of Arabidopsis phytochrome B, AtPHYBY276H or AtYHB, encodes a polypeptide that adopts a light‐insensitive, physiologically active conformation capable of sustaining photomorphogenesis in darkness.
Wei Hu +3 more
doaj +1 more source